Generalised and partial
lipodystrophy (GL and PL)

Lipodystrophy is a rare and severe disorder characterised by either partial or generalised loss of fatty tissue under the skin. This can result in a feeling of extreme hunger, a disturbance in the way the body uses and stores fat and other metabolic changes such as increased sugar and triglyceride levels in the blood. Because of its rarity and complex presentation, lipodystrophy is often diagnosed late or misdiagnosed as diabetes or other conditions. Many patients suffer from the effects of lipodystrophy for many years before receiving a correct diagnosis and access to appropriate treatment.


Because lipodystrophy is rare, doctors and patients may be unfamiliar with the signs and symptoms.
Find out more about these


Although lipodystrophy is incurable, different treatment approaches can be helpful in dealing with the complications


Do you have questions concerning lipodystrophy? Here you can find patient organisations and specialist centres for getting help and support

Is it generalised or partial lipodystrophy?
Find out more about the typical signs. Public Area

Might my patient be suffering from generalised or partial lipodystrophy?
Click below to find further information Health Care Professional Area

Date of preparation January 2023